Interactor 1: DPOLA (P13382)
DNA polymerase alpha catalytic subunit A (EC 2.7.7.7) (DNA polymerase I subunit A) (DNA polymerase alpha:primase complex p180 subunit) (DNA polymerase-primase complex p180 subunit) (Pol alpha-primase complex p180 subunit)
Gene: POL1
Interactor 2: DPOA2 (P38121)
DNA polymerase alpha subunit B (DNA polymerase I subunit B) (DNA polymerase alpha:primase complex p86 subunit) (Pol alpha-primase complex p86 subunit) (DNA polymerase-primase complex p74 subunit)
Gene: POL12
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.976 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8621497, 11805826, 16429126, 18719252, 19494830, 37344454, 37766847, 21715379, 22593576, 16554755, 37968396 |
| Identification Methods | coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, two hybrid, x-ray crystallography, biochemical, pull down |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_pol_E_B~zf-DNA_Pol, Pol_alpha_B_N~zf-DNA_Pol |
| Common GO terms | GO:0005658 - alpha DNA polymerase:primase complex GO:0006270 - DNA replication initiation |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
