Protein: VPS4
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)

Gene: VPS4
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P52917

Gene Ontology (top 5):
GO:0001778 - plasma membrane repair
GO:0005524 - ATP binding
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm
GO:0005768 - endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

915375

VPS4
Vacuolar protein sorting-associated protein 4

10

17

Small-scale

0.976

High

915383

VTA1
Vacuolar protein sorting-associated protein VTA1

20

0

Small-scale

0.940

High

727181

HS104
Heat shock protein 104

2

3

High-throughput

0.759

High

915378

DID2
Vacuolar protein-sorting-associated protein 46

12

20

Small-scale

0.759

High

815036

SNF7
Vacuolar-sorting protein SNF7

12

20

Small-scale

0.758

High

915382

VPS20
Vacuolar protein sorting-associated protein 20

8

18

Small-scale

0.752

High

781329

DID4
DOA4-independent degradation protein 4

6

20

Small-scale

0.739

High

874372

BRO1
Vacuolar-sorting protein BRO1

6

5

Small-scale

0.728

High

915377

IST1
Vacuolar protein sorting-associated protein IST1

4

8

Small-scale

0.686

High

818371

VFA1
VPS4-associated protein 1

4

0

Small-scale

0.670

High

915386

PALA
pH-response regulator protein palA/RIM20

2

5

Small-scale

0.613

High

804302

SSZ1
Ribosome-associated complex subunit SSZ1

2

6

High-throughput

0.588

High

781012

VPS24
Vacuolar protein-sorting-associated protein 24

2

20

Small-scale

0.584

High

527184

HSP72
Heat shock protein SSA2

2

10

High-throughput

0.552

High

821976

PSA6
Proteasome subunit alpha type-6

1

20

Small-scale

0.528

High

803457

OSH7
Oxysterol-binding protein homolog 7

1

2

Small-scale

0.527

High

597509

EF3A
Elongation factor 3A

1

3

High-throughput

0.515

High

657111

IF5A1
Eukaryotic translation initiation factor 5A-1

1

2

High-throughput

0.515

High

915387

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

5

High-throughput

0.515

High

915379

OSH6
Oxysterol-binding protein homolog 6

1

2

Small-scale

0.501

High

805612

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

393039

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

579743

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

739412

ZUO1
Zuotin

1

6

Small-scale

0.479

High

815177

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

5

High-throughput

0.479

High

915376

HST2
NAD-dependent protein deacetylase HST2

1

3

High-throughput

0.479

High

915380

ADA2
SAGA complex subunit ADA2

1

1

High-throughput

0.464

High

864571

YJE9
Uncharacterized protein YJL049W

1

0

Small-scale

0.460

High

915384

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

High-throughput

0.458

High

915385

VPS68
Vacuolar protein sorting-associated protein 68

1

0

High-throughput

0.458

High

898909

INP52
Polyphosphatidylinositol phosphatase INP52

1

2

High-throughput

0.457

High

386789

TBB
Tubulin beta chain

1

20

High-throughput

0.445

High

394727

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

524569

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

545569

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

741979

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

819266

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

797973

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.438

High

594469

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.437

High

707648

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

836787

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

792872

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.417

High

858029

RSSA2
Small ribosomal subunit protein uS2B

1

3

High-throughput

0.407

High

794946

YBI1
Uncharacterized protein YBL081W

1

0

High-throughput

0.269

Low

865206

MRX12
MIOREX complex component 12

1

0

High-throughput

0.265

Low

915381

HEH2
Inner nuclear membrane protein HEH2

1

0

Small-scale

0.249

Low

864932

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025