Interactor 1: TBP (P13393)
TATA-box-binding protein (TATA sequence-binding protein) (TBP) (TATA-binding factor) (TATA-box factor) (Transcription factor D) (Transcription initiation factor TFIID TBP subunit)
Gene: SPT15

Interactor 2: TF2B (P29055)
Transcription initiation factor IIB (General transcription factor TFIIB) (Transcription factor E)
Gene: SUA7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.977

The method score is based on:

Property Details
Experiments 8629014, 8374298, 8132551, 15888545, 8657139, 11048951, 17680779, 19098311, 11223526, 8516312, 7604282, 37863410
Identification Methods x-ray crystallography, pull down, biochemical, two hybrid, far western blotting, affinity chromatography technology
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TBP~TFIIB
Common GO terms GO:0000979 - RNA polymerase II core promoter sequence-specific DNA binding
GO:0005634 - nucleus
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0051123 - RNA polymerase II preinitiation complex assembly
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 240
Sc

1 345
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Last updated: 15 Jul 2024