HitPredict

Interactor 1: STIP1 (P31948)
Stress-induced-phosphoprotein 1 (STI1) (Hsc70/Hsp90-organizing protein) (Hop) (Renal carcinoma antigen NY-REN-11) (Transformation-sensitive protein IEF SSP 3521)
Gene: STIP1

Interactor 2: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	33239621, 38334954
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP70~TPR_11, HSP70~TPR_12, HSP70~TPR_8
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 639
+	Hs
		731003 STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00		HS71L_HUMAN (2-639): 0: 952: 81.90
+	Hs
		536600 STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		600747 STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00		HSP76_HUMAN (2-639): 0: 945: 77.45
+	At
		1441393 HSOP1_ARATH (3-543): 1.42e-93: 298: 41.78		HS704_ARATH (3-639): 0: 950: 73.99
+	Hs
		516183 STIP1_HUMAN (1-543): 2.06e-97: 307: 100.00		HS71B_HUMAN (3-639): 0: 933: 83.18
+	Dm
		538280 Q9VPN5_DROME (1-542): 1.57e-75: 249: 47.42		HSP7D_DROME (3-615): 0: 930: 83.36
+	Hs
		600897 SGTB_HUMAN (213-348): 5.7e-32: 126: 31.39		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Hs
		931079 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HSP72_HUMAN (1-639): 0: 954: 100.00
+	Hs
		1198774 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		Q53FA3_HUMAN (2-639): 0: 953: 81.75
+	Hs
		761494 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HS71L_HUMAN (2-639): 0: 952: 81.90
+	Hs
		537771 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Hs
		600911 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Hs
		761411 TOM34_HUMAN (1-119): 8.16e-23: 100: 26.05		HS71L_HUMAN (2-639): 0: 952: 81.90
+	Hs
		516174 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HS71A_HUMAN (3-639): 0: 933: 83.18
+	Hs
		516209 DNJC7_HUMAN (209-487): 2.86e-26: 114: 18.28		HS71B_HUMAN (3-639): 0: 933: 83.18
+	Hs
		600938 RPAP3_HUMAN (2-129): 4.51e-20: 96.2: 28.91		HSP76_HUMAN (2-639): 0: 945: 77.45
+	Hs
		185383 OGT1_HUMAN (5-241): 5.34e-17: 86.9: 12.24		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Dm
		538272 Q9VJD4_DROME (215-353): 5.38e-21: 96: 24.46		HSP7D_DROME (3-615): 0: 930: 83.36
+	Hs
		317978 TOM70_HUMAN (216-543): 8.73e-13: 73.1: 10.73		HSP7C_HUMAN (3-616): 0: 946: 87.95
+	Sc
		481463 STI1_YEAST (2-181): 4.89e-14: 76.9: 18.13		HSP73_YEAST (7-639): 0: 914: 72.22