Interactor 1: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Interactor 2: SPTCB (Q00963)
Spectrin beta chain
Gene: beta-Spec

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.866

The method score is based on:

Property Details
Experiments 11076973, 7971971, 25381248, unassigned4
Identification Methods affinity chromatography technology, pull down, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CH~EF-hand_7, CH~EFhand_Ca_insen, EFhand_Ca_insen~Spectrin, CH~Spectrin, Spectrin~Spectrin
Common GO terms GO:0005516 - calmodulin binding
GO:0005886 - plasma membrane
GO:0007026 - negative regulation of microtubule depolymerization
GO:0007274 - neuromuscular synaptic transmission
GO:0008017 - microtubule binding
and 14 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 2415
Dm

1 2291
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Rn
+ Hs
+ Dm
+ Dm
+ Dm
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024