HitPredict

Interactor 1: BMP1 (P13497)
Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
Gene: BMP1

Interactor 2: DEF1 (P59665)
Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)]
Gene: DEFA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 986 Hs			1 94
+	Hs
		234426 NRP2_HUMAN (858-984): 8.38e-25: 113: 27.61		DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00
+	Hs
		887079 LRP12_HUMAN (871-981): 2.28e-19: 96.1: 29.20		DEF1_HUMAN (1-94): 1.04e-44: 141: 100.00
+	Hs
		234427 NRP2_HUMAN (858-984): 8.38e-25: 113: 27.61		DEF5_HUMAN (1-94): 4.72e-33: 111: 48.94