HitPredict

Interactor 1: CCL5 (P13501)
C-C motif chemokine 5 (EoCP) (Eosinophil chemotactic cytokine) (SIS-delta) (Small-inducible cytokine A5) (T cell-specific protein P228) (TCP228) (T-cell-specific protein RANTES) [Cleaved into: RANTES(3-68); RANTES(4-68)]
Gene: CCL5

Interactor 2: CXCR3 (P49682)
C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)
Gene: CXCR3

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9660793
Identification Methods	biochemical
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0005737 - cytoplasm GO:0006935 - chemotaxis GO:0006954 - inflammatory response GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 91 Hs			1 368
+	Hs
		486239 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR5_HUMAN (39-366): 2e-87: 269: 31.94
+	Hs
		561733 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR5_HUMAN (39-366): 2e-87: 269: 31.94
+	Hs
		526565 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR5_HUMAN (39-366): 2e-87: 269: 31.94
+	Hs
		849654 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR5_HUMAN (39-366): 2e-87: 269: 31.94
+	Hs
		486237 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45
+	Hs
		561732 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45
+	Hs
		526564 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45
+	Hs
		849619 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR3_HUMAN (43-336): 1.14e-80: 252: 33.45
+	Hs
		830629 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CXCR3_HUMAN (1-368): 8.13e-79: 247: 100.00
+	Hs
		783833 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		CCR2_HUMAN (15-343): 3.42e-73: 233: 32.42
+	Hs
		486231 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CXCR5_HUMAN (11-365): 1.07e-70: 227: 38.23
+	Hs
		486230 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR1_HUMAN (41-368): 9.11e-70: 224: 30.27
+	Hs
		526561 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CXCR5_HUMAN (11-365): 1.07e-70: 227: 38.23
+	Hs
		561728 CL3L1_HUMAN (1-91): 2.63e-37: 121: 46.74		CCR1_HUMAN (41-368): 9.11e-70: 224: 30.27
+	Hs
		1305163 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR4_HUMAN (18-364): 8.56e-71: 226: 30.14
+	Hs
		526560 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		CCR1_HUMAN (41-368): 9.11e-70: 224: 30.27
+	Hs
		486238 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		CCR4_HUMAN (11-337): 6.64e-68: 219: 33.33
+	Hs
		134354 CCL3_HUMAN (1-91): 3.36e-37: 121: 49.45		ACKR2_HUMAN (43-333): 3.36e-50: 174: 37.42
+	Hs
		134356 CCL4_HUMAN (1-91): 1.04e-35: 118: 45.65		ACKR2_HUMAN (43-333): 3.36e-50: 174: 37.42
+	Hs
		134400 CCL13_HUMAN (1-90): 5.7e-36: 118: 31.87		ACKR2_HUMAN (43-333): 3.36e-50: 174: 37.42