HitPredict

Interactor 1: CP2C8 (P10632)
Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase)
Gene: CYP2C8

Interactor 2: CP2C8 (P10632)
Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase)
Gene: CYP2C8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.50 1.00 0.710

The method score is based on:

Property Details
Experiments 14676196
Identification Methods x-ray crystallography, pull down
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains p450~p450
Common GO terms GO:0002933 - lipid hydroxylation
GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane
and 20 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 490
Hs

1 490
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+ Oc
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025