Protein: CP2C8
Cytochrome P450 2C8 (EC 1.14.14.1) (CYPIIC8) (Cytochrome P450 IIC2) (Cytochrome P450 MP-12) (Cytochrome P450 MP-20) (Cytochrome P450 form 1) (S-mephenytoin 4-hydroxylase)

Gene: CP2C8, CYP2C8
Organism: Homo sapiens
Interactions: 24
UniProt ID: P10632

Gene Ontology (top 5):
GO:0002933 - lipid hydroxylation
GO:0004497 - monooxygenase activity
GO:0005506 - iron ion binding
GO:0005737 - cytoplasm
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

528910

CP2C8
Cytochrome P450 2C8

1

12

Small-scale

0.710

High

528913

CP2CI
Cytochrome P450 2C18

1

12

High-throughput

0.691

High

528920

RIN3
Ras and Rab interactor 3

2

0

High-throughput

0.551

High

387366

APOE
Apolipoprotein E

1

1

High-throughput

0.541

High

528926

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

4

High-throughput

0.541

High

528912

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.518

High

528918

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.518

High

129967

PGRC1
Membrane-associated progesterone receptor component 1

1

9

Small-scale

0.515

High

528911

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.515

High

369599

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.494

High

528914

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.494

High

528917

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.493

High

528927

SHLB1
Endophilin-B1

1

0

High-throughput

0.493

High

528915

PSN1
Presenilin-1

1

1

High-throughput

0.481

High

528922

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

2

High-throughput

0.481

High

166751

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

1

0

High-throughput

0.460

High

528919

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.460

High

528916

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.458

High

528921

AP2M1
AP-2 complex subunit mu

1

0

High-throughput

0.458

High

528924

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

528923

RNF32
RING finger protein 32

1

1

High-throughput

0.439

High

528925

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

1

High-throughput

0.407

High

280476

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025