HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	31324722
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 377
+	Hs
		529215 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTBL_HUMAN (4-377): 0: 712: 87.97
+	Hs
		528863 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTB_HUMAN (4-377): 0: 598: 94.12
+	Hs
		528948 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTG_HUMAN (4-377): 0: 598: 94.39
+	Hs
		528949 CFTR_HUMAN (1-1480): 0: 1031: 100.00		ACTH_HUMAN (4-377): 0: 591: 99.20