Interactor 1: CP2D6 (P10635)
Cytochrome P450 2D6 (EC 1.14.14.-) (CYPIID6) (Cholesterol 25-hydroxylase) (Cytochrome P450-DB1) (Debrisoquine 4-hydroxylase)
Gene: CYP2D6
Interactor 2: NCPR (P16435)
NADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
Gene: POR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15680923 |
| Identification Methods | pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Flavodoxin_1~p450 |
| Common GO terms | GO:0005789 - endoplasmic reticulum membrane GO:0006805 - xenobiotic metabolic process GO:0043231 - intracellular membrane-bounded organelle |
| Homologous interactions | 6 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
