HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: RCN2 (Q14257)
Reticulocalbin-2 (Calcium-binding protein ERC-55) (E6-binding protein) (E6BP)
Gene: RCN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.50	0.604

Property	Details
Experiments	26618866, 17110338, 29924966
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 317
+	Hs
		216161 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALU_HUMAN (1-313): 5.78e-60: 195: 35.51
+	Hs
		529150 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RCN1_HUMAN (31-317): 1.33e-49: 169: 37.98
+	Hs
		484052 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALM3_HUMAN (219-316): 3.06e-18: 81.6: 22.45
+	Hs
		528591 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALL3_HUMAN (219-316): 5.46e-15: 72.7: 20.41
+	Hs
		529820 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CALL5_HUMAN (152-287): 4.49e-09: 56.2: 26.47
+	Dm
		1182022 Q7KTD0_DROME (788-1466): 6.87e-53: 206: 14.95		Q8IRH7_DROME (123-311): 4.41e-50: 166: 33.85