HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0019899 - enzyme binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 475
+	Mm
		530708 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		U2AF2_MOUSE (1-475): 1.57e-95: 298: 99.79
+	Hs
		529861 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV1_HUMAN (149-471): 2.79e-73: 235: 14.79
+	Hs
		529716 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV2_HUMAN (116-470): 1.27e-71: 232: 13.42
+	Hs
		529799 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV3_HUMAN (127-472): 2.41e-67: 222: 13.98
+	Hs
		529798 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		RBM39_HUMAN (10-471): 4.96e-48: 175: 19.16
+	Hs
		590245 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		U2AF2_HUMAN (1-475): 2.14e-95: 297: 100.00
+	Hs
		529124 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		ELAV4_HUMAN (88-342): 3.41e-39: 147: 13.33
+	Hs
		529183 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TIA1_HUMAN (253-475): 7.07e-37: 141: 16.14
+	Hs
		530532 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PUF60_HUMAN (92-474): 7.88e-23: 103: 21.50
+	Mm
		530830 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		ELAV4_MOUSE (88-342): 3.41e-39: 147: 13.33
+	Hs
		529736 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP4_HUMAN (41-251): 1.15e-19: 94.2: 12.78
+	Hs
		528957 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PABP1_HUMAN (41-247): 2e-19: 93.4: 14.35
+	Mm
		530733 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		TIA1_MOUSE (253-475): 5.22e-37: 141: 16.14
+	Rn
		620110 TAU_RAT (1-758): 3.21e-76: 263: 72.11		PUF60_RAT (92-474): 7.8e-23: 103: 21.96
+	Hs
		685692 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		U2AF2_HUMAN (1-475): 2.14e-95: 297: 100.00
+	Rn
		620098 TAU_RAT (1-758): 3.21e-76: 263: 72.11		PABP1_RAT (41-247): 2.62e-19: 93: 14.35
+	Rn
		98792 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		PABP1_RAT (41-247): 2.62e-19: 93: 14.35
+	Mm
		530834 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		Q62029_MOUSE (41-259): 2.69e-17: 86.5: 13.19
+	Hs
		1126882 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		RBM39_HUMAN (10-471): 4.96e-48: 175: 19.16
+	Hs
		1127095 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RBM39_HUMAN (10-471): 4.96e-48: 175: 19.16