HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: EEA1 (Q15075)
Early endosome antigen 1 (Endosome-associated protein p162) (Zinc finger FYVE domain-containing protein 2)
Gene: EEA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	29924966
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol GO:0031901 - early endosome membrane GO:0055037 - recycling endosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 1411
+	Hs
		529896 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH13_HUMAN (688-1396): 1.13e-31: 137: 14.21
+	Hs
		528682 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH11_HUMAN (788-1407): 6.15e-29: 128: 13.11
+	Hs
		528676 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH10_HUMAN (774-1399): 1.27e-26: 121: 14.86
+	Hs
		522586 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH7_HUMAN (1-591): 2.75e-25: 116: 12.80
+	Hs
		528357 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH6_HUMAN (724-1397): 4.68e-25: 116: 13.09
+	Hs
		528400 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH8_HUMAN (1-596): 2.84e-25: 116: 13.98
+	Hs
		529972 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH4_HUMAN (1-595): 1.57e-23: 111: 13.83
+	Hs
		502902 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH3_HUMAN (778-1399): 7.96e-23: 108: 13.43
+	Hs
		528675 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH9_HUMAN (953-1410): 9.73e-18: 92.2: 13.07
+	Hs
		64579 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH7B_HUMAN (778-1392): 5.75e-16: 86: 11.63
+	Hs
		529895 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH2_HUMAN (3-413): 8.73e-15: 82.2: 12.83
+	Hs
		522533 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MYH1_HUMAN (3-413): 1.32e-14: 81.8: 11.89
+	Hs
		528484 CFTR_HUMAN (1-1480): 0: 1031: 100.00		DESP_HUMAN (566-1354): 5.18e-13: 76.6: 19.23