HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome subunit alpha-5) (alpha-5) (Proteasome zeta chain)
Gene: PSMA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 241
+	Hs
		165244 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PSA7_HUMAN (8-239): 5.33e-89: 265: 36.17
+	Hs
		529114 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PSA1_HUMAN (3-241): 7.76e-89: 265: 28.81
+	Hs
		529115 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PSA2_HUMAN (3-241): 2.39e-89: 265: 30.96
+	Hs
		529467 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93
+	Mm
		530931 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		PSA6_MOUSE (4-241): 1.12e-87: 261: 25.93
+	Hs
		165380 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		PSA7_HUMAN (8-239): 5.33e-89: 265: 36.17