Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SYUA (P37840)
Alpha-synuclein (Non-A beta component of AD amyloid) (Non-A4 component of amyloid precursor) (NACP)
Gene: SNCA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 10464279, 36634849, 39079530, 32291284, 35063084, 21985244, 15904919, 21127069, 32814053
Identification Methods biochemical, proximity labelling technology, two hybrid, pull down, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001774 - microglial cell activation
GO:0003779 - actin binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 11 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 758
Hs

1 140
+ Hs
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Service provided by Combinatics, Japan

Last updated: 11Aug2025