HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26618866
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1480 Hs			1 618
+	Hs
		529384 CFTR_HUMAN (1-1480): 0: 1031: 100.00		MIRO1_HUMAN (1-618): 0: 763: 59.65
+	Hs
		528476 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		528868 CFTR_HUMAN (1-1480): 0: 1031: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		528936 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		528909 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		528880 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		436139 CFTR_HUMAN (1-1480): 0: 1031: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		545225 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		706692 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		706693 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		706711 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		706705 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		706702 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		706699 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		706700 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		706695 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		706733 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436176 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120319 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564426 MRP1_HUMAN (810-1471): 5.31e-60: 229: 15.70		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26