HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: ATX2L (Q8WWM7)
Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein)
Gene: ATXN2L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	17110338, 31324722
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 1075
+	Hs
		528824 CFTR_HUMAN (1-1480): 0: 1031: 100.00		SC24C_HUMAN (613-1018): 1.53e-10: 67.5: 11.79
+	Dm
		954676 L259_DROME (42-639): 1.85e-59: 227: 15.27		Q9VLS7_DROME (383-1039): 5.1e-11: 69.5: 10.03
+	Dm
		1370370 Q9W2I5_DROME (51-671): 1.32e-52: 205: 14.15		Q9VLS7_DROME (383-1039): 5.1e-11: 69.5: 10.03