HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: TBA1C (Q9BQE3)
Tubulin alpha-1C chain (EC 3.6.5.-) (Alpha-tubulin 6) (Tubulin alpha-6 chain) [Cleaved into: Detyrosinated tubulin alpha-1C chain]
Gene: TUBA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 449
+	Hs
		528957 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBA4A_HUMAN (1-448): 0: 724: 96.21
+	Hs
		528956 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBA1B_HUMAN (1-439): 0: 717: 99.09
+	Hs
		529319 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBA1A_HUMAN (1-439): 0: 715: 99.09
+	Hs
		427992 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB5_HUMAN (1-439): 0: 699: 41.00
+	Hs
		529805 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBA8_HUMAN (1-439): 0: 698: 90.66
+	Hs
		528958 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB4B_HUMAN (1-437): 0: 697: 40.73
+	Hs
		529674 CFTR_HUMAN (1-1480): 0: 1031: 100.00		TBB2B_HUMAN (1-440): 0: 697: 40.23