Protein: CDK5
Cyclin-dependent kinase 5 homolog (EC 2.7.11.22) (Cell division protein kinase 5)

Gene: CDK5
Organism: Drosophila melanogaster
Interactions: 53
UniProt ID: P48609

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

668152

CCNC
Cyclin-C

2

20

High-throughput

0.785

High

875377

Q9VE37
Mitogen-activated protein kinase kinase kinase 4

1

11

Small-scale

0.724

High

875359

CCNE
G1/S-specific cyclin-E

1

20

High-throughput

0.656

High

875379

Q9VGK8
Tyrosine-protein kinase

1

15

High-throughput

0.656

High

875390

Q9VZP3
Cyclin J, isoform A

1

20

High-throughput

0.656

High

875392

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.656

High

875366

Q7KUZ5
Cyclin D, isoform D

1

20

High-throughput

0.621

High

875370

Q8MSQ4
Mitogen-activated protein kinase kinase kinase 4

1

10

Small-scale

0.618

High

875375

Q9V3H5
Cyclin-dependent kinase 5 activator

1

7

Small-scale

0.618

High

875364

Q7K306
cyclin-dependent kinase

1

15

High-throughput

0.590

High

875388

Q9VXM1
LD22957p

1

20

High-throughput

0.590

High

875397

Q9W3K8
EF-hand domain-containing protein

1

8

High-throughput

0.587

High

55514

A1Z9G1
FI19824p1

1

8

High-throughput

0.555

High

458217

DFD
Homeotic protein deformed

1

10

High-throughput

0.508

High

609093

CRN
Protein crooked neck

1

2

High-throughput

0.508

High

627197

DLL
Homeotic protein distal-less

1

7

High-throughput

0.508

High

756439

ECR
Ecdysone receptor

1

10

High-throughput

0.508

High

875362

RAD51
DNA repair protein Rad51 homolog

1

2

High-throughput

0.508

High

875365

ACOX1
Acyl-coenzyme A oxidase 1

1

1

High-throughput

0.508

High

875373

ENA
Protein enabled

1

5

High-throughput

0.508

High

875374

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.508

High

875378

Q9VFQ3
E5

1

9

High-throughput

0.508

High

875381

Q9VL21
LD11652p

1

4

High-throughput

0.508

High

875382

Q9VL27
Alpha-galactosidase

1

1

High-throughput

0.508

High

875385

NUBP2
Cytosolic Fe-S cluster assembly factor Nubp2 homolog

1

1

High-throughput

0.508

High

875376

NPL4
Nuclear protein localization protein 4 homolog

1

0

High-throughput

0.486

High

875367

PANG2
Protein pangolin, isoform J

1

5

High-throughput

0.481

High

875394

Q9W1H7
Putative homeodomain protein

1

4

High-throughput

0.481

High

715082

CLH
Clathrin heavy chain

1

2

High-throughput

0.464

High

875384

POLZ2
DNA polymerase zeta subunit 2

1

1

High-throughput

0.464

High

875391

Q9W022
GEO01508p1

1

9

High-throughput

0.464

High

875386

Q9VQ95
Testis EndoG-Like 3

1

0

High-throughput

0.460

High

303722

O76136
Homeodomain protein

1

8

High-throughput

0.457

High

875361

CPN
Calphotin

1

5

High-throughput

0.457

High

875369

UBP2
Ubiquitin carboxyl-terminal hydrolase Usp2

1

6

High-throughput

0.457

High

875383

PSB4
Proteasome subunit beta type-4

1

8

High-throughput

0.457

High

53300

A1Z7M3
Notopleural, isoform A

1

1

High-throughput

0.439

High

95621

E3CTS2
MIP27658p

1

3

High-throughput

0.439

High

875400

X2JLM6
Ubiquitin carboxyl-terminal hydrolase

1

6

High-throughput

0.439

High

875360

PANG1
Protein pangolin, isoforms A/H/I/S

1

3

High-throughput

0.417

High

875371

Q8SYU4
RE33778p

1

3

High-throughput

0.417

High

875399

Q9Y138
BcDNA.GH06193

1

8

High-throughput

0.417

High

234831

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

875363

Q4V5L1
IP07030p

1

0

High-throughput

0.265

Low

875368

Q8IMG8
FI22218p1

1

0

High-throughput

0.265

Low

875372

Q8SZP2
RE71854p

1

0

High-throughput

0.265

Low

875380

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.265

Low

875387

Q9VRQ4
LD47944p

1

0

High-throughput

0.265

Low

875389

COMDA
COMM domain-containing protein 10 homolog Vlet

1

0

High-throughput

0.265

Low

875393

Q9W0Y0
RE57840p

1

0

High-throughput

0.265

Low

875395

Q9W1P1
Cilia- and flagella-associated protein 61 N-terminal domain-containing protein

1

0

High-throughput

0.265

Low

875396

Q9W221
MIP04282p

1

0

High-throughput

0.265

Low

875398

NEP3
Neprilysin-3

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025