HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: CAND1 (Q86VP6)
Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1)
Gene: CAND1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1230
+	Rn
		620053 TAU_RAT (1-758): 3.21e-76: 263: 72.11		CAND1_RAT (1-1230): 0: 920: 99.76
+	Rn
		98743 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		CAND1_RAT (1-1230): 0: 920: 99.76
+	Mm
		530843 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		CAND1_MOUSE (1-1230): 0: 920: 99.43
+	Hs
		133930 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		IPO5_HUMAN (145-1127): 4.62e-35: 147: 10.95
+	Hs
		164517 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TNPO2_HUMAN (432-1148): 1.54e-15: 84.2: 12.59
+	Hs
		530151 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GCN1_HUMAN (8-396): 2.84e-11: 70.4: 12.69
+	Hs
		530173 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TNPO1_HUMAN (826-1148): 1.52e-09: 64.6: 12.21
+	Hs
		133935 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		IPO5_HUMAN (145-1127): 4.62e-35: 147: 10.95
+	Hs
		286039 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		SF3B1_HUMAN (365-1153): 1.41e-55: 214: 12.32