HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: SYN2 (Q92777)
Synapsin-2 (Synapsin II)
Gene: SYN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0050808 - synapse organization
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 582
+	Rn
		620075 TAU_RAT (1-758): 3.21e-76: 263: 72.11		SYN2_RAT (1-582): 0: 724: 92.19
+	Rn
		98768 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		SYN2_RAT (1-582): 0: 724: 92.19
+	Hs
		529025 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SYN1_HUMAN (2-582): 0: 581: 49.58
+	Rn
		488666 TAU_RAT (1-758): 3.21e-76: 263: 72.11		SYN1_RAT (2-582): 0: 609: 49.93
+	Rn
		98659 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		SYN1_RAT (2-582): 0: 609: 49.93
+	Mm
		313171 MTAP2_MOUSE (26-758): 2.26e-30: 131: 24.41		SYN1_MOUSE (2-582): 0: 607: 49.51
+	Hs
		116433 H7BXF5_HUMAN (4-689): 3.27e-24: 111: 8.33		SYN1_HUMAN (2-582): 0: 581: 49.58
+	Hs
		530335 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		TMPSD_HUMAN (431-581): 2.04e-11: 68.7: 11.26
+	Dm
		119660 M9PB30_DROME (3-585): 4.93e-18: 91.6: 9.03		M9PB30_DROME (384-581): 5.14e-09: 61.7: 13.16
+	Hs
		130585 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		SPT5H_HUMAN (400-531): 3.95e-09: 61.7: 15.86
+	Hs
		130304 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		SPT5H_HUMAN (400-531): 3.95e-09: 61.7: 15.86
+	Mm
		1455913 PCLO_MOUSE (31-654): 3.4e-09: 62.7: 10.40		PCLO_MOUSE (398-578): 4.62e-09: 61.7: 13.74