HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: COR2B (Q9UQ03)
Coronin-2B (Coronin-like protein C) (Clipin-C) (Protein FC96)
Gene: CORO2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 480
+	Hs
		530569 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR1C_HUMAN (9-473): 3.92e-115: 348: 44.63
+	Hs
		529179 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR1A_HUMAN (9-476): 3.15e-110: 335: 43.76
+	Hs
		530296 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR1B_HUMAN (6-480): 1.77e-109: 334: 42.00
+	Hs
		1401446 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		COR1C_HUMAN (9-473): 3.92e-115: 348: 44.63
+	Hs
		529882 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		RBBP7_HUMAN (82-167): 1.48e-12: 71.2: 20.43
+	Hs
		529702 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		RBBP4_HUMAN (83-167): 4.19e-12: 69.7: 19.57
+	Dm
		1039718 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		Q9W3W1_DROME (15-469): 6.57e-73: 251: 25.44
+	Dm
		94614 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		D6W4T8_DROME (15-469): 4.6e-72: 249: 25.44
+	Hs
		161490 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		POC1A_HUMAN (3-301): 3.06e-74: 241: 13.20
+	Hs
		698256 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Hs
		965173 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Hs
		161443 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		WDR5_HUMAN (211-449): 5.78e-34: 132: 10.16
+	Hs
		1129693 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		SNR40_HUMAN (263-453): 8.9e-18: 86.5: 11.22
+	Hs
		1149790 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		TAF5_HUMAN (181-345): 5.78e-19: 92: 11.22
+	Hs
		1380165 PRR36_HUMAN (3-683): 5.21e-13: 75.1: 9.08		FBXW7_HUMAN (19-161): 1.27e-13: 75.4: 13.33
+	Hs
		698338 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		FBXW7_HUMAN (19-161): 1.27e-13: 75.4: 13.33
+	Ce
		594158 RPB1_CAEEL (82-426): 1e-10: 67.6: 14.12		LIN53_CAEEL (20-167): 1.02e-12: 71.6: 19.75
+	Hs
		1158968 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RBBP7_HUMAN (82-167): 1.48e-12: 71.2: 20.43
+	Hs
		1066453 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RBBP4_HUMAN (83-167): 4.19e-12: 69.7: 19.57
+	Hs
		161486 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		WDR5B_HUMAN (299-452): 3.94e-09: 59.9: 5.63