HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: COR1C (Q9ULV4)
Coronin-1C (Coronin-3) (hCRNN4)
Gene: CORO1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 474
+	Hs
		530296 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR1B_HUMAN (2-472): 5.26e-123: 369: 71.73
+	Hs
		529179 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR1A_HUMAN (2-467): 2.42e-115: 348: 64.24
+	Hs
		1401446 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		COR1C_HUMAN (1-474): 1.23e-137: 406: 100.00
+	Hs
		530595 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COR2B_HUMAN (4-218): 7.95e-25: 108: 10.57
+	Hs
		529702 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Dm
		1039718 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		Q9W3W1_DROME (4-447): 2.91e-91: 301: 28.83
+	Hs
		530063 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		WDR17_HUMAN (79-205): 4.99e-10: 64.3: 29.69
+	Hs
		529882 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08
+	Hs
		161490 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		POC1A_HUMAN (2-294): 1.18e-73: 239: 16.38
+	Hs
		161486 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		WDR5B_HUMAN (124-395): 3.11e-54: 186: 15.33
+	Hs
		1129693 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		SNR40_HUMAN (2-200): 4.35e-40: 149: 18.72
+	Ce
		594158 RPB1_CAEEL (82-426): 1e-10: 67.6: 14.12		LIN53_CAEEL (67-296): 5.82e-21: 96.7: 17.01
+	Hs
		1066453 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RBBP4_HUMAN (79-296): 5.06e-20: 94: 20.78
+	Hs
		698256 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		965173 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		161443 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Hs
		965097 KMT2C_HUMAN (228-752): 7.28e-09: 62: 7.94		WDR5_HUMAN (2-109): 1.96e-16: 82.3: 14.29
+	Mm
		965395 KMT2C_MOUSE (228-587): 6.08e-09: 61.9: 16.84		WDR5_MOUSE (2-109): 1.96e-16: 82.3: 14.29
+	Dm
		94614 CPN_DROME (353-756): 7.79e-12: 70.8: 13.55		D6W4T8_DROME (4-228): 1.81e-10: 65.7: 12.66
+	Hs
		1158968 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		RBBP7_HUMAN (25-113): 2.71e-10: 64.2: 23.08