HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: ERLN2 (Q8BFZ9)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: Erlin2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045121 - membrane raft
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 340
+	Mm
		530780 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		PHB1_MOUSE (1-263): 1.62e-65: 209: 18.80
+	Mm
		204265 TAU_MOUSE (1-733): 2.37e-87: 292: 100.00		PHB2_MOUSE (5-263): 9.62e-63: 203: 14.83
+	Rn
		620072 TAU_RAT (1-733): 4.65e-79: 270: 88.06		PHB2_RAT (5-263): 7.04e-63: 203: 14.83
+	Rn
		98764 F1LST4_RAT (1-732): 7.83e-79: 270: 88.18		PHB2_RAT (5-263): 7.04e-63: 203: 14.83
+	Hs
		529132 TAU_HUMAN (1-733): 5e-62: 223: 69.69		STOM_HUMAN (4-249): 4.04e-69: 219: 17.13
+	Hs
		529209 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PHB1_HUMAN (1-263): 3.06e-65: 208: 18.80
+	Hs
		530269 TAU_HUMAN (1-733): 5e-62: 223: 69.69		PHB2_HUMAN (5-263): 9.62e-63: 203: 14.83
+	Hs
		698228 MAP4_HUMAN (26-726): 1.81e-32: 137: 21.70		PHB1_HUMAN (1-263): 3.06e-65: 208: 18.80
+	Hs
		766723 ATX2L_HUMAN (23-632): 8.89e-27: 119: 11.68		PHB1_HUMAN (1-263): 3.06e-65: 208: 18.80
+	Hs
		1129713 MDC1_HUMAN (25-730): 2.08e-16: 86.2: 8.73		PHB2_HUMAN (5-263): 9.62e-63: 203: 14.83