Interactor 1: GFAP (P14136)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Interactor 2: DESM (P17661)
Desmin
Gene: DES

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 28514442, 32296183, 34079125, 33961781, 32814053, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005829 - cytosol
GO:0005882 - intermediate filament
GO:0045109 - intermediate filament organization
GO:0045111 - intermediate filament cytoskeleton
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 432
Hs

1 470
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024