Interactor 1: HGF (P14210)
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]
Gene: HGF

Interactor 2: HGFA (Q04756)
Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain]
Gene: HGFAC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 20004165
Identification Methods protease assay
Interaction Type direct interaction, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Kringle~Kringle, Kringle~Trypsin, Kringle~PAN_1, PAN_1~Trypsin, EGF~Trypsin, Trypsin~Trypsin
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 728
Hs

1 655
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024