Protein: TAF6
Transcription initiation factor TFIID subunit 6 (TBP-associated factor 6) (TBP-associated factor 60 kDa) (TAFII-60) (TAFII60)

Gene: TAF6
Organism: Saccharomyces cerevisiae S288C
Interactions: 169
UniProt ID: P53040

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

744654

TAF5
Transcription initiation factor TFIID subunit 5

21

9

Small-scale

0.988

High

858570

TAF9
Transcription initiation factor TFIID subunit 9

15

8

Small-scale

0.986

High

858582

HFI1
Transcriptional coactivator HFI1/ADA1

12

1

Small-scale

0.977

High

858556

H3
Histone H3

2

5

Small-scale

0.776

High

715360

SPT7
Transcriptional activator SPT7

22

16

Small-scale

0.766

High

805214

TAF1
Transcription initiation factor TFIID subunit 1

20

3

Small-scale

0.765

High

858558

ADA2
Transcriptional adapter 2

19

4

Small-scale

0.764

High

858564

TAF12
Transcription initiation factor TFIID subunit 12

16

5

Small-scale

0.762

High

858562

GCN5
Histone acetyltransferase GCN5

14

12

Small-scale

0.762

High

691330

NGG1
Chromatin-remodeling complexes subunit NGG1

14

1

Small-scale

0.760

High

355945

H2B2
Histone H2B.2

2

2

Small-scale

0.759

High

858580

TAF10
Transcription initiation factor TFIID subunit 10

13

5

Small-scale

0.759

High

420616

SPT3
Protein SPT3

10

5

Small-scale

0.756

High

527031

TBP
TATA-box-binding protein

10

6

Small-scale

0.753

High

837441

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

10

3

Small-scale

0.753

High

633878

SGF29
SAGA-associated factor 29

8

1

Small-scale

0.750

High

858567

TAF11
Transcription initiation factor TFIID subunit 11

8

4

Small-scale

0.750

High

858550

SGF73
SAGA-associated factor 73

8

2

Small-scale

0.749

High

613861

TAF2
Transcription initiation factor TFIID subunit 2

8

1

Small-scale

0.748

High

858569

TAF7
Transcription initiation factor TFIID subunit 7

7

3

Small-scale

0.747

High

837491

TAF4
Transcription initiation factor TFIID subunit 4

7

3

Small-scale

0.746

High

515119

TAF13
Transcription initiation factor TFIID subunit 13

8

5

Small-scale

0.746

High

755434

TRA1
Transcription-associated protein 1

7

4

Small-scale

0.745

High

858596

SUS1
Transcription and mRNA export factor SUS1

6

1

Small-scale

0.732

High

757442

SPT8
Transcription factor SPT8

13

0

Small-scale

0.728

High

842067

SPT20
Transcription factor SPT20

13

0

Small-scale

0.728

High

355550

H2B1
Histone H2B.1

2

2

Small-scale

0.712

High

715709

TAF14
Transcription initiation factor TFIID subunit 14

5

1

Small-scale

0.709

High

858588

TAF3
Transcription initiation factor TFIID subunit 3

6

0

Small-scale

0.701

High

858563

TAF8
Transcription initiation factor TFIID subunit 8

6

0

Small-scale

0.700

High

858560

SGF11
SAGA-associated factor 11

6

0

Small-scale

0.697

High

858548

TAF6
Transcription initiation factor TFIID subunit 6

3

2

Small-scale

0.656

High

687720

BTAF1
TATA-binding protein-associated factor MOT1

3

4

Small-scale

0.640

High

423694

ADR1
Regulatory protein ADR1

2

1

Small-scale

0.621

High

679751

PSK1
Serine/threonine-protein kinase PSK1

2

1

High-throughput

0.621

High

767626

GLE2
mRNA export factor GLE2

1

2

High-throughput

0.618

High

392157

H2A1
Histone H2A.1

1

1

Small-scale

0.618

High

587869

AP1
AP-1-like transcription factor YAP1

2

0

High-throughput

0.602

High

544093

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.601

High

707033

MSN4
Zinc finger protein MSN4

2

1

High-throughput

0.601

High

430787

SYV
Valine--tRNA ligase, mitochondrial

2

0

High-throughput

0.595

High

507803

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

2

0

High-throughput

0.595

High

343843

SYMC
Methionine--tRNA ligase, cytoplasmic

2

1

High-throughput

0.588

High

650340

SPT5
Transcription elongation factor SPT5

2

0

High-throughput

0.585

High

381562

GAL4
Regulatory protein GAL4

2

2

Small-scale

0.576

High

368750

GCN4
General control transcription factor GCN4

2

0

Small-scale

0.576

High

858595

H2AZ
Histone H2A.Z

1

2

High-throughput

0.575

High

772298

ATAD2
ATPase histone chaperone YTA7

2

1

High-throughput

0.571

High

628766

RNA14
mRNA 3'-end-processing protein RNA14

2

0

High-throughput

0.563

High

693600

MED22
Mediator of RNA polymerase II transcription subunit 22

2

0

High-throughput

0.563

High

858578

MED7
Mediator of RNA polymerase II transcription subunit 7

2

0

High-throughput

0.563

High

858593

NOT5
General negative regulator of transcription subunit 5

2

0

Small-scale

0.559

High

728723

BDF1
Bromodomain-containing factor 1

1

13

Small-scale

0.554

High

515072

MCM1
Pheromone receptor transcription factor

2

0

High-throughput

0.547

High

628275

SIS1
Protein SIS1

2

0

High-throughput

0.547

High

680864

HS104
Heat shock protein 104

2

0

High-throughput

0.547

High

689913

ASF1
Histone chaperone ASF1

2

0

Small-scale

0.547

High

858587

RIO1
Serine/threonine-protein kinase RIO1

2

0

High-throughput

0.547

High

334506

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

1

High-throughput

0.536

High

334960

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

1

High-throughput

0.536

High

357531

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.536

High

366603

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.536

High

560736

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.536

High

676216

XPO1
Exportin-1

1

1

High-throughput

0.536

High

858586

HAL9
Halotolerance protein 9

1

2

High-throughput

0.536

High

858590

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.536

High

858585

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.515

High

416795

CDC31
Cell division control protein 31

1

0

Small-scale

0.513

High

519611

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.513

High

534801

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.513

High

537456

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.513

High

554696

HSP26
Heat shock protein 26

1

0

High-throughput

0.513

High

599868

DIT1
Spore wall maturation protein DIT1

1

0

High-throughput

0.513

High

627647

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.513

High

693332

RPN2
26S proteasome regulatory subunit RPN2

1

0

High-throughput

0.513

High

703693

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.513

High

710662

SEF1
Putative transcription factor SEF1

1

0

High-throughput

0.513

High

732751

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.513

High

771722

PRS4
26S proteasome regulatory subunit 4 homolog

1

0

High-throughput

0.513

High

774481

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.513

High

858561

MTG1
Mitochondrial GTPase 1

1

0

High-throughput

0.513

High

858575

SUB2
ATP-dependent RNA helicase SUB2

1

0

High-throughput

0.513

High

858577

THP1
Nuclear mRNA export protein THP1

1

0

Small-scale

0.513

High

822703

RFX1
RFX-like DNA-binding protein RFX1

1

1

Small-scale

0.501

High

516309

RAP1
DNA-binding protein RAP1

1

0

Small-scale

0.494

High

399771

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.489

High

399902

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.489

High

496071

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.489

High

645766

INO2
Protein INO2

1

0

Small-scale

0.480

High

477377

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

479618

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.479

High

697415

CHD1
Chromo domain-containing protein 1

1

2

Small-scale

0.479

High

778552

SAS2
Histone acetyltransferase SAS2

1

1

Small-scale

0.479

High

858555

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.479

High

858566

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

376858

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.458

High

407189

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

478930

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

481187

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.458

High

481376

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.458

High

481949

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.458

High

558158

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

645547

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

662788

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688331

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700994

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

706378

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

716291

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716470

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

751053

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

762389

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

775785

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

805114

SAC3
Nuclear mRNA export protein SAC3

1

0

Small-scale

0.458

High

812047

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

858553

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

858571

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

858572

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

858583

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

858584

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

356600

H4
Histone H4

1

2

High-throughput

0.445

High

408409

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.445

High

419362

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

457046

SWI6
Regulatory protein SWI6

1

1

High-throughput

0.445

High

479658

RS30B
Small ribosomal subunit protein eS30B

1

1

High-throughput

0.445

High

628877

SWI4
Regulatory protein SWI4

1

1

High-throughput

0.445

High

695108

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

706977

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

733271

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

768945

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

858554

CRZ1
Transcriptional regulator CRZ1

1

1

High-throughput

0.445

High

858557

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

11

High-throughput

0.445

High

858559

HOS3
Histone deacetylase HOS3

1

3

High-throughput

0.445

High

548619

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.438

High

404640

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

452114

SWI1
SWI/SNF chromatin-remodeling complex subunit SWI1

1

0

High-throughput

0.426

High

498998

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

605241

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

696719

RTG1
Retrograde regulation protein 1

1

0

High-throughput

0.426

High

770093

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

784173

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

858565

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.426

High

858573

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.426

High

858576

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

858589

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

High-throughput

0.426

High

858591

RLF2
Chromatin assembly factor 1 subunit p90

1

0

High-throughput

0.426

High

858581

RCN2
Regulator of calcineurin 2

1

0

High-throughput

0.282

High

251774

TIM9
Mitochondrial import inner membrane translocase subunit TIM9

1

0

High-throughput

0.279

Low

333855

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.279

Low

360960

TBB
Tubulin beta chain

1

0

High-throughput

0.279

Low

389956

VDAC1
Mitochondrial outer membrane protein porin 1

1

0

High-throughput

0.279

Low

399553

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

453013

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

485776

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.279

Low

614520

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

0

High-throughput

0.279

Low

677100

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.279

Low

812518

CAF17
Putative transferase CAF17, mitochondrial

1

0

High-throughput

0.279

Low

858549

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.279

Low

858551

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.279

Low

858574

MRL1
Mannose 6-phosphate receptor-like protein 1

1

0

High-throughput

0.279

Low

858579

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

1

0

High-throughput

0.279

Low

858592

NOP58
Nucleolar protein 58

1

0

High-throughput

0.279

Low

858594

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.279

Low

858597

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.279

Low

858568

GFD1
mRNA transport factor GFD1

1

0

High-throughput

0.265

Low

549436

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

805261

TFC5
Transcription factor TFIIIB component B''

1

0

High-throughput

0.249

Low

858552

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

774776

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024