HitPredict

Interactor 1: UBC3 (P14682)
Ubiquitin-conjugating enzyme E2-34 kDa (EC 2.3.2.23) (Cell division control protein 34) (E2 ubiquitin-conjugating enzyme 3) (E3 ubiquitin ligase complex SCF subunit CDC34) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: CDC34

Interactor 2: RBX1 (Q08273)
RING-box protein HRT1 (RING-box protein 1) (E3 ubiquitin-protein ligase complex SCF subunit HRT1) (High level expression reduces Ty3 transposition protein 1) (Regulator of cullins protein 1)
Gene: HRT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 10213692, 12553912, 13678584, 14747994, 9346238, 9285816, 21098119, 10385629, 27697924, 32804080, 25982115, 34700328, 35920641, 36161924, 16360039, 19945379, 17574027, 20542006, 22328159, 20194622 and 1 others

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Identification Methods coimmunoprecipitation, pull down, affinity chromatography technology, fluorescent resonance energy transfer, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UQ_con~zf-rbx1
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000409 - regulation of transcription by galactose
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
and 14 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 295
Sc

1 121
+ Ce
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024