Protein: CEA21
Cell adhesion molecule CEACAM21 (Carcinoembryonic antigen-related cell adhesion molecule 21) (CEA cell adhesion molecule 21)

Gene: CEA21, CEACAM21
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q3KPI0

Gene Ontology (top 5):
GO:0006955 - immune response
GO:0009897 - external side of plasma membrane
GO:0042110 - T cell activation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834665

TNFL9
Tumor necrosis factor ligand superfamily member 9

3

1

High-throughput

0.861

High

1186229

ULBP3
UL16-binding protein 3

3

8

High-throughput

0.861

High

1186204

CD276
CD276 antigen

2

18

High-throughput

0.811

High

719720

HLAF
HLA class I histocompatibility antigen, alpha chain F

2

6

High-throughput

0.789

High

472073

MET
Hepatocyte growth factor receptor

3

15

High-throughput

0.770

High

522673

PTPRF
Receptor-type tyrosine-protein phosphatase F

3

14

High-throughput

0.770

High

626000

ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2

3

4

High-throughput

0.770

High

932081

EPHA4
Ephrin type-A receptor 4

3

10

High-throughput

0.770

High

1088147

CNTN1
Contactin-1

3

10

High-throughput

0.770

High

1102710

PTPRS
Receptor-type tyrosine-protein phosphatase S

3

17

High-throughput

0.770

High

1109454

ATR
Serine/threonine-protein kinase ATR

3

3

High-throughput

0.770

High

1186200

CDON
Cell adhesion molecule-related/down-regulated by oncogenes

3

11

High-throughput

0.770

High

1186202

SDK2
Protein sidekick-2

3

14

High-throughput

0.770

High

1186208

FAT4
Protocadherin Fat 4

3

14

High-throughput

0.770

High

1186215

PCD20
Protocadherin-20

3

8

High-throughput

0.770

High

1186242

KDIS
Kinase D-interacting substrate of 220 kDa

3

4

High-throughput

0.770

High

1186243

PCDGK
Protocadherin gamma-C3

3

2

High-throughput

0.770

High

1186245

PCDGB
Protocadherin gamma-A11

3

2

High-throughput

0.770

High

1186236

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

4

0

High-throughput

0.746

High

1186226

ABHEA
Protein ABHD14A

3

0

High-throughput

0.720

High

710633

EPHA3
Ephrin type-A receptor 3

2

8

High-throughput

0.705

High

1186206

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

11

High-throughput

0.705

High

1186235

ABCB6
ATP-binding cassette sub-family B member 6

2

1

High-throughput

0.705

High

520868

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

6

High-throughput

0.691

High

654977

ITA6
Integrin alpha-6

1

8

High-throughput

0.691

High

1186201

LRC24
Leucine-rich repeat-containing protein 24

1

18

High-throughput

0.691

High

1186224

HMR1
Major histocompatibility complex class I-related protein 1

1

6

High-throughput

0.691

High

1186230

ULBP1
UL16-binding protein 1

1

8

High-throughput

0.691

High

1120618

DAG1
Dystroglycan 1

3

2

High-throughput

0.667

High

554228

BMP4
Bone morphogenetic protein 4

1

3

High-throughput

0.618

High

580778

PVR
Poliovirus receptor

1

15

High-throughput

0.618

High

640181

EPHA1
Ephrin type-A receptor 1

1

8

High-throughput

0.618

High

1036987

DSC2
Desmocollin-2

1

6

High-throughput

0.618

High

1062170

PCDH1
Protocadherin-1

1

15

High-throughput

0.618

High

1062980

DDR1
Epithelial discoidin domain-containing receptor 1

1

12

High-throughput

0.618

High

1186216

CADM4
Cell adhesion molecule 4

1

14

High-throughput

0.618

High

1186220

SCRB1
Scavenger receptor class B member 1

1

1

High-throughput

0.618

High

1186232

TOR3A
Torsin-3A

1

2

High-throughput

0.618

High

1186234

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

13

High-throughput

0.618

High

1186240

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

11

High-throughput

0.618

High

557335

SRC
Proto-oncogene tyrosine-protein kinase Src

3

8

High-throughput

0.609

High

761235

RYK
Tyrosine-protein kinase RYK

3

13

High-throughput

0.609

High

1022862

EFNB1
Ephrin-B1

3

2

High-throughput

0.609

High

1186218

GOGA5
Golgin subfamily A member 5

3

6

High-throughput

0.609

High

1186219

CIP2A
Protein CIP2A

3

2

High-throughput

0.609

High

380754

HBD
Hemoglobin subunit delta

1

0

High-throughput

0.578

High

409406

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

6

High-throughput

0.575

High

649182

GALA
Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide

2

1

High-throughput

0.558

High

876687

HSP13
Heat shock 70 kDa protein 13

2

2

High-throughput

0.558

High

409577

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

8

High-throughput

0.553

High

541521

FGFR1
Fibroblast growth factor receptor 1

1

19

High-throughput

0.553

High

1101731

PTK7
Inactive tyrosine-protein kinase 7

1

20

High-throughput

0.553

High

1186222

NECT2
Nectin-2

1

18

High-throughput

0.553

High

1186233

PCDH9
Protocadherin-9

1

15

High-throughput

0.553

High

156280

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

1

High-throughput

0.489

High

164738

HS3S1
Heparan sulfate glucosamine 3-O-sulfotransferase 1

1

2

High-throughput

0.489

High

1186203

ODR4
Protein odr-4 homolog

1

1

High-throughput

0.489

High

1186205

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

2

High-throughput

0.489

High

1186227

TMM59
Transmembrane protein 59

1

1

High-throughput

0.489

High

1186237

UFSP2
Ufm1-specific protease 2

1

1

High-throughput

0.489

High

1186238

CC50A
Cell cycle control protein 50A

1

1

High-throughput

0.489

High

1186207

MOXD1
DBH-like monooxygenase protein 1

1

1

High-throughput

0.437

High

1186214

KCD17
BTB/POZ domain-containing protein KCTD17

1

5

High-throughput

0.407

High

1186210

OAF
Out at first protein homolog

3

0

High-throughput

0.347

High

1186217

TIP
T-cell immunomodulatory protein

3

0

High-throughput

0.347

High

1186225

MITOK
Mitochondrial potassium channel

3

0

High-throughput

0.347

High

1186228

FUT8
Alpha-(1,6)-fucosyltransferase

3

0

High-throughput

0.347

High

1186239

PDXL2
Podocalyxin-like protein 2

3

0

High-throughput

0.347

High

1186241

S53A1
Solute carrier family 53 member 1

3

0

High-throughput

0.347

High

866378

MSS4
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.279

Low

1186209

DPPA4
Developmental pluripotency-associated protein 4

1

0

High-throughput

0.279

Low

1186212

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low

1186221

LIPH
Lipase member H

1

0

High-throughput

0.279

Low

1186231

INT2
Integrator complex subunit 2

1

0

High-throughput

0.279

Low

1186244

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.279

Low

1186211

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.249

Low

1186213

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.249

Low

1186223

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.249

Low

1121008

VGLL4
Transcription cofactor vestigial-like protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025