Interactor 1: MBL2 (P11226)
Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)
Gene: MBL2
Interactor 2: MASP1 (P48740)
Mannan-binding lectin serine protease 1 (EC 3.4.21.-) (Complement factor MASP-3) (Complement-activating component of Ra-reactive factor) (Mannose-binding lectin-associated serine protease 1) (MASP-1) (Mannose-binding protein-associated serine protease) (Ra-reactive factor serine protease p100) (RaRF) (Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain]
Gene: MASP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.60 | 0.755 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10878362, 25579818, 11290788, 32041782, 20956340, 22854970, 22607836, 27104295, 19939495, 21035894 |
| Identification Methods | affinity chromatography technology, molecular sieving, 3D electron microscopy, x ray scattering, surface plasmon resonance, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation, solid phase assay |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0001867 - complement activation, lectin pathway GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0006508 - proteolysis GO:0048306 - calcium-dependent protein binding |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
