Protein: MBL2
Mannose-binding protein C (MBP-C) (Collectin-1) (MBP1) (Mannan-binding protein) (Mannose-binding lectin)

Gene: MBL2
Organism: Homo sapiens
Interactions: 43
UniProt ID: P11226

Gene Ontology (top 5):
GO:0001867 - complement activation, lectin pathway
GO:0002752 - cell surface pattern recognition receptor signaling pathway
GO:0005102 - signaling receptor binding
GO:0005537 - D-mannose binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

539653

MBL2
Mannose-binding protein C

5

18

Small-scale

0.922

High

126287

TLR4
Toll-like receptor 4

2

13

Small-scale

0.819

High

539663

MASP1
Mannan-binding lectin serine protease 1

10

9

Small-scale

0.755

High

125805

MASP2
Mannan-binding lectin serine protease 2

7

10

Small-scale

0.744

High

388958

FINC
Fibronectin

1

20

Small-scale

0.647

High

191200

TLR3
Toll-like receptor 3

1

13

Small-scale

0.618

High

539683

UBQL2
Ubiquilin-2

2

4

High-throughput

0.553

High

539655

PSB1
Proteasome subunit beta type-1

1

3

High-throughput

0.536

High

539657

PSA2
Proteasome subunit alpha type-2

1

2

High-throughput

0.536

High

539679

PSB7
Proteasome subunit beta type-7

1

1

High-throughput

0.536

High

539684

LY96
Lymphocyte antigen 96

1

3

Small-scale

0.515

High

388834

APOH
Beta-2-glycoprotein 1

1

5

Small-scale

0.501

High

462738

UROM
Uromodulin

1

15

Small-scale

0.501

High

539654

CR1
Complement receptor type 1

1

12

Small-scale

0.501

High

539661

CALR
Calreticulin

1

10

Small-scale

0.501

High

539656

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.489

High

539658

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.489

High

539662

PSB4
Proteasome subunit beta type-4

1

4

High-throughput

0.489

High

539664

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.489

High

539665

PSB2
Proteasome subunit beta type-2

1

3

High-throughput

0.489

High

539666

PSA6
Proteasome subunit alpha type-6

1

2

High-throughput

0.489

High

539669

PDIA5
Protein disulfide-isomerase A5

1

6

High-throughput

0.489

High

539671

PCGF3
Polycomb group RING finger protein 3

1

3

High-throughput

0.489

High

539674

RSLBA
Ras-like protein family member 11A

1

4

High-throughput

0.489

High

539675

FBX11
F-box only protein 11

1

3

High-throughput

0.489

High

539677

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

1

High-throughput

0.489

High

539678

FUBP3
Far upstream element-binding protein 3

1

1

High-throughput

0.489

High

539680

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.489

High

539681

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

3

High-throughput

0.489

High

388575

SAMP
Serum amyloid P-component

1

3

Small-scale

0.479

High

539659

PTX3
Pentraxin-related protein PTX3

1

3

Small-scale

0.479

High

539682

SLTM
SAFB-like transcription modulator

1

6

High-throughput

0.470

High

407370

K2C1
Keratin, type II cytoskeletal 1

1

0

Small-scale

0.458

High

539673

DCAF6
DDB1- and CUL4-associated factor 6

1

3

High-throughput

0.437

High

539667

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.426

High

539668

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

Small-scale

0.279

Low

289752

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

539660

DCK
Deoxycytidine kinase

1

0

High-throughput

0.279

Low

539670

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.279

Low

539672

SPIN4
Spindlin-4

1

0

High-throughput

0.279

Low

539676

TF2LX
Homeobox protein TGIF2LX

1

0

High-throughput

0.279

Low

515671

TPC2B
Trafficking protein particle complex subunit 2B

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025