Interactor 1: BRAF (P15056)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (p94) (v-Raf murine sarcoma viral oncogene homolog B1)
Gene: BRAF

Interactor 2: MAPK3 (Q16644)
MAP kinase-activated protein kinase 3 (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAP-K3) (MAPKAPK-3) (MK-3) (EC 2.7.11.1) (Chromosome 3p kinase) (3pK)
Gene: MAPKAPK3

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 24412244
Identification Methods two hybrid array
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase
Common GO terms GO:0004674 - protein serine/threonine kinase activity
GO:0004708 - MAP kinase kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 766
Hs

1 382
+ At
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ At
+ Hs

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Last updated: 15 Jul 2024