HitPredict

Interactor 1: UBL4A (P11441)
Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
Gene: UBL4A

Interactor 2: KPCA (P17252)
Protein kinase C alpha type (PKC-A) (PKC-alpha) (EC 2.7.11.13)
Gene: PRKCA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 157 Hs			1 672
+	Hs
		507501 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCA_HUMAN (1-672): 0: 802: 100.00
+	Rn
		998171 UBC_RAT (1-102): 9.5e-29: 112: 31.13		KPCB_RAT (1-664): 0: 752: 79.34
+	Hs
		436588 UBB_HUMAN (1-76): 1.44e-29: 109: 39.47		KPCB_HUMAN (1-664): 0: 754: 78.89
+	Hs
		436589 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCB_HUMAN (1-664): 0: 754: 78.89
+	Hs
		436647 RL40_HUMAN (1-72): 8.02e-29: 104: 41.67		KPCB_HUMAN (1-664): 0: 754: 78.89
+	Rn
		993951 UBC_RAT (1-102): 9.5e-29: 112: 31.13		KPCG_RAT (16-670): 0: 706: 69.88
+	Rn
		479898 UBC_RAT (1-102): 9.5e-29: 112: 31.13		KPCE_RAT (8-664): 0: 629: 43.41
+	Hs
		986995 RS27A_HUMAN (1-123): 2.92e-40: 134: 28.46		KPCE_HUMAN (8-664): 0: 600: 41.02
+	Hs
		728152 RS27A_HUMAN (1-123): 2.92e-40: 134: 28.46		AKT1_HUMAN (245-660): 4.41e-157: 463: 37.53
+	Hs
		507093 UBB_HUMAN (1-76): 1.44e-29: 109: 39.47		AKT2_HUMAN (240-660): 2.41e-157: 464: 38.95
+	Hs
		507092 UBB_HUMAN (1-76): 1.44e-29: 109: 39.47		AKT1_HUMAN (245-660): 4.41e-157: 463: 37.53
+	Hs
		507582 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		AKT1_HUMAN (245-660): 4.41e-157: 463: 37.53
+	Hs
		728153 RL40_HUMAN (1-72): 8.02e-29: 104: 41.67		AKT1_HUMAN (245-660): 4.41e-157: 463: 37.53
+	Hs
		122905 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		SGK1_HUMAN (255-661): 1.68e-153: 452: 38.85
+	Rn
		479892 UBC_RAT (1-102): 9.5e-29: 112: 31.13		KPCD_RAT (9-178): 1.7e-55: 202: 36.67
+	Mm
		509099 UBC_MOUSE (1-102): 1.78e-28: 111: 31.13		KPCI_MOUSE (22-108): 6.88e-34: 139: 36.78
+	Hs
		507645 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCI_HUMAN (22-86): 8.67e-12: 70.1: 43.08
+	Hs
		507864 UBC_HUMAN (1-77): 1.92e-27: 108: 40.26		KPCZ_HUMAN (22-98): 3.22e-11: 68.6: 34.44