HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: TSA1 (P34760)
Peroxiredoxin TSA1 (Prx) (EC 1.11.1.24) (Cytoplasmic thiol peroxidase 1) (cTPx 1) (Protector protein) (PRP) (Thiol-specific antioxidant protein 1) (Thioredoxin peroxidase type Ia) (TPx type Ia) (Thioredoxin-dependent peroxide reductase) (Thioredoxin-dependent peroxiredoxin TSA1)
Gene: TSA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31399574, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0034605 - cellular response to heat GO:0050821 - protein stabilization and 1 others more... GO:0051082 - unfolded protein binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 196
+	Sc
		366081 HSP82_YEAST (1-705): 0: 968: 95.63		TSA1_YEAST (1-196): 3.79e-93: 271: 100.00
+	Sc
		544358 HSC82_YEAST (1-705): 0: 977: 100.00		TSA2_YEAST (1-195): 2.04e-88: 259: 86.15
+	Sc
		366839 HSP82_YEAST (1-705): 0: 968: 95.63		TSA2_YEAST (1-195): 2.04e-88: 259: 86.15
+	Sc
		543494 HSC82_YEAST (1-705): 0: 977: 100.00		PRX1_YEAST (3-196): 8.29e-70: 214: 28.16