HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: LYS12 (P40495)
Homoisocitrate dehydrogenase, mitochondrial (HIcDH) (EC 1.1.1.87)
Gene: LYS12

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31399574, 37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 371
+	Sc
		366412 HSP82_YEAST (1-705): 0: 968: 95.63		LYS12_YEAST (1-371): 1.6e-151: 433: 100.00
+	Sc
		543320 HSC82_YEAST (1-705): 0: 977: 100.00		IDH2_YEAST (2-371): 2.68e-141: 407: 33.95
+	Sc
		543332 HSC82_YEAST (1-705): 0: 977: 100.00		IDH1_YEAST (3-371): 2.95e-138: 399: 34.41
+	Sc
		365911 HSP82_YEAST (1-705): 0: 968: 95.63		IDH2_YEAST (2-371): 2.68e-141: 407: 33.95
+	Sc
		365923 HSP82_YEAST (1-705): 0: 968: 95.63		IDH1_YEAST (3-371): 2.95e-138: 399: 34.41
+	Sc
		378270 HSC82_YEAST (1-705): 0: 977: 100.00		LEU3_YEAST (25-371): 7.77e-113: 335: 31.25
+	Sc
		365512 HSP82_YEAST (1-705): 0: 968: 95.63		LEU3_YEAST (25-371): 7.77e-113: 335: 31.25
+	Dm
		1361640 Q9VAY2_DROME (3-676): 0: 833: 47.09		IDH3A_DROME (5-371): 1.6e-159: 453: 33.33