HitPredict

Interactor 1: INSR (P15127)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: COPD (Q66H80)
Coatomer subunit delta (Archain) (Delta-coat protein) (Delta-COP)
Gene: Arcn1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	25687571, 30300385
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1383 Rn			1 511
+	Rn
		1146015 T2CB11_RAT (1-1383): 0: 1570: 99.42		COPD_RAT (1-511): 0: 830: 100.00
+	Hs
		411333 INSR_HUMAN (27-1383): 0: 1527: 95.43		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		818906 EPHA5_HUMAN (662-1320): 0: 581: 24.11		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		818944 EPHA7_HUMAN (664-1321): 0: 568: 22.55		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		665450 EPHA8_HUMAN (663-1323): 1.14e-174: 548: 22.59		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		445830 ROS1_HUMAN (1020-1292): 1.06e-71: 267: 49.46		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		819048 ALK_HUMAN (997-1340): 6.12e-71: 264: 41.57		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		169166 MUSK_HUMAN (1018-1292): 3.32e-69: 253: 42.22		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		384466 NTRK1_HUMAN (997-1287): 1.6e-65: 240: 41.95		COPD_HUMAN (1-511): 0: 825: 98.83
+	Hs
		818949 NTRK3_HUMAN (997-1291): 5.26e-62: 230: 38.80		COPD_HUMAN (1-511): 0: 825: 98.83