Interactor 1: PVR (P15151)
Poliovirus receptor (Nectin-like protein 5) (NECL-5) (CD antigen CD155)
Gene: PVR

Interactor 2: ACE2 (Q9BYF1)
Angiotensin-converting enzyme 2 (EC 3.4.17.23) (Angiotensin-converting enzyme homolog) (ACEH) (Angiotensin-converting enzyme-related carboxypeptidase) (ACE-related carboxypeptidase) (EC 3.4.17.-) (Metalloprotease MPROT15) [Cleaved into: Processed angiotensin-converting enzyme 2]
Gene: ACE2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37499664
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M2~V-set
Common GO terms GO:0001618 - virus receptor activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0016020 - membrane
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 417
Hs

1 805
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024