Protein: AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 (AGAP-3) (CRAM-associated GTPase) (CRAG) (Centaurin-gamma-3) (Cnt-g3) (MR1-interacting protein) (MRIP-1)

Gene: AGAP3
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q96P47

Gene Ontology (top 5):
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity
GO:0005525 - GTP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

943611

HUNK
Hormonally up-regulated neu tumor-associated kinase

2

3

High-throughput

0.817

High

1279144

RHG22
Rho GTPase-activating protein 22

2

8

High-throughput

0.811

High

1358830

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

4

High-throughput

0.811

High

975183

ARF6
ADP-ribosylation factor 6

2

17

High-throughput

0.754

High

703685

MK01
Mitogen-activated protein kinase 1

2

5

High-throughput

0.737

High

1399423

RGAP1
Rac GTPase-activating protein 1

2

6

High-throughput

0.737

High

407695

S100B
Protein S100-B

1

1

High-throughput

0.691

High

832939

CETN2
Centrin-2

1

1

High-throughput

0.691

High

1399421

TANC1
Protein TANC1

1

6

High-throughput

0.691

High

1399424

RABE2
Rab GTPase-binding effector protein 2

1

3

High-throughput

0.691

High

1399427

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

13

High-throughput

0.691

High

1324708

MIER2
Mesoderm induction early response protein 2

3

4

High-throughput

0.667

High

966762

1433G
14-3-3 protein gamma

3

20

High-throughput

0.662

High

276715

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

3

0

High-throughput

0.638

High

1338827

FLCN
Folliculin

2

3

High-throughput

0.628

High

630339

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.618

High

1399422

NUAK2
NUAK family SNF1-like kinase 2

1

1

High-throughput

0.618

High

1399425

TANC2
Protein TANC2

1

6

High-throughput

0.618

High

343020

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.618

High

831265

CCNF
Cyclin-F

1

5

High-throughput

0.618

High

1255124

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.618

High

1324046

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.618

High

1399426

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

731546

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.586

High

1399420

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

0

High-throughput

0.585

High

255173

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

3

High-throughput

0.575

High

935023

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.575

High

1326037

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.575

High

1339392

GP156
Probable G-protein coupled receptor 156

2

6

High-throughput

0.574

High

1395069

JPH4
Junctophilin-4

2

3

High-throughput

0.574

High

1399419

LZTS2
Leucine zipper putative tumor suppressor 2

2

7

High-throughput

0.574

High

396744

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

412453

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.553

High

845762

MUC18
Cell surface glycoprotein MUC18

1

3

High-throughput

0.553

High

415798

HSPB1
Heat shock protein beta-1

1

7

High-throughput

0.541

High

885372

HXA1
Homeobox protein Hox-A1

1

9

High-throughput

0.541

High

74575

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.536

High

230092

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.536

High

537736

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.536

High

659561

CRCM
Colorectal mutant cancer protein

1

2

High-throughput

0.536

High

730158

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

961209

FGF12
Fibroblast growth factor 12

1

6

High-throughput

0.536

High

971895

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

1049680

1433F
14-3-3 protein eta

1

20

High-throughput

0.536

High

1123773

DCTN1
Dynactin subunit 1

1

2

High-throughput

0.536

High

1310322

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1348942

ZCH10
Zinc finger CCHC domain-containing protein 10

1

1

High-throughput

0.536

High

1383816

EFMT3
EEF1A lysine methyltransferase 3

1

5

High-throughput

0.536

High

106491

APRIO
Alternative prion protein

2

4

High-throughput

0.533

High

1399418

C10
Protein C10

1

0

High-throughput

0.513

High

155210

NCKP5
Nck-associated protein 5

1

10

High-throughput

0.489

High

718451

CD6
T-cell differentiation antigen CD6

1

2

High-throughput

0.489

High

1259060

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.489

High

1339431

NBEA
Neurobeachin

1

7

High-throughput

0.489

High

242634

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

540627

LAMP1
Lysosome-associated membrane glycoprotein 1

1

3

High-throughput

0.479

High

589450

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

696254

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

721052

CLIP1
CAP-Gly domain-containing linker protein 1

1

2

High-throughput

0.479

High

838163

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

3

Small-scale

0.479

High

970939

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

1096792

RFA4
Replication protein A 30 kDa subunit

1

6

High-throughput

0.479

High

1141269

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

1277892

NUFP2
FMR1-interacting protein NUFIP2

1

1

High-throughput

0.479

High

1367057

ESR2
Estrogen receptor beta

1

4

High-throughput

0.479

High

358781

LDHA
L-lactate dehydrogenase A chain

1

0

High-throughput

0.458

High

1399417

T22D3
TSC22 domain family protein 3

1

0

High-throughput

0.458

High

430251

JUN
Transcription factor Jun

1

7

High-throughput

0.445

High

530238

TAU
Microtubule-associated protein tau

1

11

High-throughput

0.445

High

404879

PRIO
Major prion protein

1

0

High-throughput

0.426

High

591348

CD44
CD44 antigen

1

1

High-throughput

0.407

High

1278557

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

1

3

High-throughput

0.407

High

1394877

EAF1
ELL-associated factor 1

1

1

High-throughput

0.407

High

190464

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

282534

PAGE1
P antigen family member 1

1

0

High-throughput

0.279

Low

1169539

SKDA1
SKI/DACH domain-containing protein 1

1

0

High-throughput

0.279

Low

1208323

SPXN2
Sperm protein associated with the nucleus on the X chromosome N2

1

0

High-throughput

0.279

Low

1333315

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1226230

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025