Protein: SMAP1
Stromal membrane-associated protein 1

Gene: SMAP1
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q8IYB5

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0030276 - clathrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1314747

SMAP2
Stromal membrane-associated protein 2

3

7

High-throughput

0.843

High

975116

ARF6
ADP-ribosylation factor 6

1

20

Small-scale

0.647

High

958793

ARF3
ADP-ribosylation factor 3

1

20

High-throughput

0.618

High

1314754

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.618

High

1180156

QRIC1
Transcriptional regulator QRICH1

2

2

High-throughput

0.606

High

1314753

PFD5
Prefoldin subunit 5

2

1

High-throughput

0.606

High

1314758

AIPL1
Aryl-hydrocarbon-interacting protein-like 1

2

2

High-throughput

0.606

High

320832

KLH18
Kelch-like protein 18

2

1

High-throughput

0.601

High

1314763

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.586

High

1314750

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.580

High

210049

CRX
Cone-rod homeobox protein

2

1

High-throughput

0.553

High

1314751

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

1

High-throughput

0.553

High

347161

BAG2
BAG family molecular chaperone regulator 2

2

2

High-throughput

0.549

High

1185830

ZN829
Zinc finger protein 829

1

1

High-throughput

0.536

High

1314748

ASB11
Ankyrin repeat and SOCS box protein 11

1

0

High-throughput

0.517

High

422539

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

1026124

CLH1
Clathrin heavy chain 1

1

4

Small-scale

0.501

High

608302

EGLN
Endoglin

1

0

High-throughput

0.480

High

132154

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

173046

XPO1
Exportin-1

1

12

High-throughput

0.479

High

226117

STX6
Syntaxin-6

1

5

High-throughput

0.479

High

242236

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

277374

TP4A3
Protein tyrosine phosphatase type IVA 3

1

3

High-throughput

0.479

High

363544

EGFR
Epidermal growth factor receptor

1

15

High-throughput

0.479

High

483146

CLCA
Clathrin light chain A

1

3

High-throughput

0.479

High

483364

CLCB
Clathrin light chain B

1

3

High-throughput

0.479

High

541580

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

631333

RAB5A
Ras-related protein Rab-5A

1

7

High-throughput

0.479

High

648582

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

695903

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

714258

PML
Protein PML

1

2

High-throughput

0.479

High

761445

HS71L
Heat shock 70 kDa protein 1-like

1

7

High-throughput

0.479

High

945038

RAB25
Ras-related protein Rab-25

1

7

High-throughput

0.479

High

986557

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

1034286

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.479

High

1107908

SQSTM
Sequestosome-1

1

7

High-throughput

0.479

High

1156767

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

1254566

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1314749

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

1314759

WRP73
WD repeat-containing protein WRAP73

1

3

High-throughput

0.479

High

1314760

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

1314761

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.479

High

1017651

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.470

High

590920

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

1314755

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.458

High

1314757

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

430117

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

530056

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

537486

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.445

High

930982

HSP72
Heat shock-related 70 kDa protein 2

1

7

High-throughput

0.445

High

1094367

CSN1
COP9 signalosome complex subunit 1

1

1

High-throughput

0.445

High

1209369

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

1017720

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

106242

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

589119

RFA2
Replication protein A 32 kDa subunit

1

9

High-throughput

0.437

High

768612

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1096749

RFA4
Replication protein A 30 kDa subunit

1

9

High-throughput

0.437

High

1226464

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.437

High

1276207

ATG9A
Autophagy-related protein 9A

1

1

High-throughput

0.437

High

1314752

SNX27
Sorting nexin-27

1

4

High-throughput

0.437

High

894426

MMP14
Matrix metalloproteinase-14

1

0

High-throughput

0.426

High

1314746

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

273895

CNOT3
CCR4-NOT transcription complex subunit 3

1

4

High-throughput

0.407

High

1314744

MICU2
Calcium uptake protein 2, mitochondrial

3

0

High-throughput

0.347

High

1119578

NFYC
Nuclear transcription factor Y subunit gamma

2

0

High-throughput

0.316

High

1314745

NPW
Neuropeptide W

1

0

High-throughput

0.269

Low

1138385

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.249

Low

1314762

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

217146

MS18B
Protein Mis18-beta

1

0

High-throughput

0.232

Low

229188

B3GT2
Beta-1,3-galactosyltransferase 2

1

0

High-throughput

0.232

Low

1104013

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1314756

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025