Interactor 1: INSR (P15208)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR
Interactor 2: SH2B2 (Q9JID9)
SH2B adapter protein 2 (Adapter protein with pleckstrin homology and Src homology 2 domains) (SH2 and PH domain-containing adapter protein APS)
Gene: SH2B2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.56 | 1.00 | 0.754 |
The method score is based on:
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~fn3, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2 |
| Common GO terms | GO:0005886 - plasma membrane GO:0008286 - insulin receptor signaling pathway GO:0042593 - glucose homeostasis |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
 |
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Rn | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
