Protein: HFM1
ATP-dependent DNA helicase MER3 (EC 5.6.2.4) (DNA 3'-5' helicase MER3) (Protein HFM1)

Gene: HFM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 31
UniProt ID: P51979

Gene Ontology (top 5):
GO:0000712 - resolution of meiotic recombination intermediates
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

560242

TOP3
DNA topoisomerase 3

1

1

Small-scale

0.740

High

807640

MLH1
DNA mismatch repair protein MLH1

3

3

Small-scale

0.669

High

909506

MLH2
DNA mismatch repair protein MLH2

3

3

Small-scale

0.669

High

909500

HFM1
ATP-dependent DNA helicase MER3

1

13

Small-scale

0.647

High

909507

PRP46
Pre-mRNA-splicing factor PRP46

1

18

Small-scale

0.555

High

597507

EF3A
Elongation factor 3A

1

1

High-throughput

0.515

High

660804

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

4

High-throughput

0.515

High

909505

LSM6
LSM complex subunit LSM6

1

6

High-throughput

0.508

High

909503

RMI1
RecQ-mediated genome instability protein 1

1

0

Small-scale

0.504

High

664448

MCM3
DNA replication licensing factor MCM3

1

8

Small-scale

0.479

High

672500

SYNM
Asparagine--tRNA ligase, mitochondrial

1

1

Small-scale

0.479

High

801009

RFC1
Replication factor C subunit 1

1

7

Small-scale

0.479

High

824921

TM108
Protein TMA108

1

3

Small-scale

0.479

High

826303

DOT5
Peroxiredoxin DOT5

1

1

Small-scale

0.479

High

909504

SKY1
Serine/threonine-protein kinase SKY1

1

20

Small-scale

0.479

High

454526

PIF1
ATP-dependent DNA helicase PIF1

1

0

Small-scale

0.458

High

701655

OPLA
5-oxoprolinase

1

0

Small-scale

0.458

High

820874

GAT2
Protein GAT2

1

0

Small-scale

0.458

High

524551

HSP71
Heat shock protein SSA1

1

17

High-throughput

0.445

High

527167

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

545551

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

741971

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

804301

SSZ1
Ribosome-associated complex subunit SSZ1

1

8

High-throughput

0.445

High

816307

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

536041

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

1

Small-scale

0.437

High

909502

MLP1
Protein MLP1

1

8

High-throughput

0.437

High

909501

FAR11
Factor arrest protein 11

2

0

High-throughput

0.307

High

654795

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.282

High

753254

MFT1
THO complex subunit MFT1

1

0

Small-scale

0.249

Low

799668

TPS3
Trehalose synthase complex regulatory subunit TPS3

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025