HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding GO:0051015 - actin filament binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 1025
+	Hs
		719735 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		547263 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SWP70_HUMAN (370-824): 7.27e-58: 212: 19.22
+	Hs
		547149 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		547213 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		719751 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		547100 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		148355 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		547222 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		719732 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		1329247 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		719604 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		SCAPE_HUMAN (71-937): 4.97e-45: 179: 13.95
+	Hs
		1153393 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		148455 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		640054 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		1153382 E41L1_HUMAN (3-524): 3.54e-119: 375: 23.06		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		1153473 FARP1_HUMAN (3-549): 1.97e-117: 375: 19.07		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		204680 E41L2_HUMAN (2-577): 1.05e-117: 374: 19.70		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		505568 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		505569 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH10_HUMAN (534-1014): 3.94e-16: 85.9: 9.18
+	Hs
		505542 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH1_HUMAN (122-873): 2.75e-15: 83.2: 8.13