HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: PHAR4 (Q8IZ21)
Phosphatase and actin regulator 4
Gene: PHACTR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0030036 - actin cytoskeleton organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 702
+	Hs
		547281 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MACF1_HUMAN (497-699): 3.78e-37: 152: 17.96
+	Hs
		547015 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		DYST_HUMAN (477-699): 6.74e-36: 148: 17.83
+	Hs
		719790 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		MACF1_HUMAN (497-699): 3.78e-37: 152: 17.96
+	Hs
		719702 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		DYST_HUMAN (477-699): 6.74e-36: 148: 17.83
+	Hs
		1223918 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		PHAR4_HUMAN (1-702): 3.04e-73: 252: 100.00
+	Hs
		203207 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SYNJ1_HUMAN (12-354): 5.61e-10: 65: 10.98
+	Hs
		297816 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		K0754_HUMAN (100-652): 9.48e-20: 97: 10.70
+	Hs
		974150 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		DYST_HUMAN (477-699): 6.74e-36: 148: 17.83
+	Hs
		1336313 E41L3_HUMAN (2-466): 2.17e-114: 367: 22.83		CHD8_HUMAN (71-636): 1.81e-26: 118: 10.56
+	Hs
		297842 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		K0754_HUMAN (100-652): 9.48e-20: 97: 10.70