Interactor 1: GCN2 (P15442)
eIF-2-alpha kinase GCN2 (EC 2.7.11.1) (General control non-derepressible protein 2) (Serine/threonine-protein kinase GCN2)
Gene: GCN2

Interactor 2: GCN1 (P33892)
eIF-2-alpha kinase activator GCN1 (General control non-derepressible protein 1) (Translational activator GCN1)
Gene: GCN1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.720

The method score is based on:

Property Details
Experiments 11350982, 10801780, 10775272, 19448108, 21849502
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0022626 - cytosolic ribosome
GO:0031369 - translation initiation factor binding
GO:0034198 - cellular response to amino acid starvation
GO:0043022 - ribosome binding
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1659
Sc

1 2672
+ Hs
+ At
+ Hs
+ At
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024