Interactor 1: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Interactor 2: SMAD4 (Q13485)
Mothers against decapentaplegic homolog 4 (MAD homolog 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (SMAD family member 4) (SMAD 4) (Smad4) (hSMAD4)
Gene: SMAD4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 0.60 0.601

The method score is based on:

Property Details
Experiments 11486006, 18952601
Identification Methods electrophoretic mobility shift assay, electrophoretic mobility supershift assay, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001541 - ovarian follicle development
GO:0001666 - response to hypoxia
GO:0001701 - in utero embryonic development
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 395
Hs

1 552
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024