Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: DNLI1 (P18858)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: LIG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 12171929, 9649448, 24958773
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_ligase_A_N~PCNA_C, DNA_ligase_A_N~PCNA_N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006287 - base-excision repair, gap-filling
GO:0006298 - mismatch repair
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 261
Hs

1 919
+ Sp
+ Sc
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025