Protein: DNLI1
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)

Gene: DNLI1, CDC9
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: P04819

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0003677 - DNA binding
GO:0003910 - DNA ligase (ATP) activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

416790

PCNA
Proliferating cell nuclear antigen

6

5

Small-scale

0.944

High

416801

FEN1
Flap endonuclease 1

1

0

Small-scale

0.614

High

394080

EF1A
Elongation factor 1-alpha

2

1

High-throughput

0.584

High

416792

VATB
V-type proton ATPase subunit B

2

3

High-throughput

0.584

High

416785

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

416787

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

416805

RAD24
Checkpoint protein RAD24

1

5

Small-scale

0.536

High

416815

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.536

High

416833

DBP9
ATP-dependent RNA helicase DBP9

1

0

High-throughput

0.513

High

416780

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

366864

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.500

High

416776

ATPA
ATP synthase subunit alpha, mitochondrial

1

3

High-throughput

0.500

High

416779

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.500

High

416786

METK1
S-adenosylmethionine synthase 1

1

1

High-throughput

0.500

High

416794

HXKG
Glucokinase-1

1

1

High-throughput

0.500

High

416796

METK2
S-adenosylmethionine synthase 2

1

1

High-throughput

0.500

High

416798

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.500

High

416788

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

0

High-throughput

0.493

High

416782

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.480

High

408261

GAL1
Galactokinase

1

0

High-throughput

0.479

High

416775

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.479

High

416795

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.479

High

416807

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

416834

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

416803

MCM4
DNA replication licensing factor MCM4

1

1

Small-scale

0.479

High

416811

RFC5
Replication factor C subunit 5

1

3

Small-scale

0.479

High

416812

RFC3
Replication factor C subunit 3

1

3

Small-scale

0.479

High

416813

RFC1
Replication factor C subunit 1

1

3

Small-scale

0.479

High

416817

RFC4
Replication factor C subunit 4

1

4

Small-scale

0.479

High

416818

RFC2
Replication factor C subunit 2

1

3

Small-scale

0.479

High

416830

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.479

High

416797

YCP7
DUP240 protein DFP3

1

1

High-throughput

0.464

High

416824

PRM8
Pheromone-regulated membrane protein 8

1

1

High-throughput

0.464

High

416777

CBP8
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.458

High

416793

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

416802

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

416804

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

416806

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

416808

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

416809

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

416810

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

416820

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

416826

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

Small-scale

0.458

High

416828

YMH9
Uncharacterized protein YML079W

1

0

High-throughput

0.458

High

416831

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

416832

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

416836

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

416837

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

416838

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

386505

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

391958

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

416781

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

416783

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.445

High

416784

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

416816

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

416778

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

416819

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

416823

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

416827

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.426

High

416835

AMF1
Low affinity ammonium transporter

1

0

High-throughput

0.279

Low

416825

PRA1
Prenylated Rab acceptor 1

1

0

High-throughput

0.265

Low

416829

TVP15
Golgi apparatus membrane protein TVP15

1

0

High-throughput

0.265

Low

416791

ABP1
Actin-binding protein

1

0

High-throughput

0.261

Low

416789

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.261

Low

416814

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

416799

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

416800

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.232

Low

416821

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

416822

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025