HitPredict

Interactor 1: KCRB (P12277)
Creatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B)
Gene: CKB

Interactor 2: KCRU (P12532)
Creatine kinase U-type, mitochondrial (EC 2.7.3.2) (Acidic-type mitochondrial creatine kinase) (Mia-CK) (Ubiquitous mitochondrial creatine kinase) (U-MtCK)
Gene: CKMT1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	35235311, 34349018, 36652389
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ATP-gua_Ptrans~ATP-gua_Ptrans, ATP-gua_Ptrans~ATP-gua_PtransN, ATP-gua_PtransN~ATP-gua_PtransN
Common GO terms	GO:0004111 - creatine kinase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0046314 - phosphocreatine biosynthetic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 417
+	Hs
		445641 KCRM_HUMAN (1-381): 0: 635: 80.58		KCRU_HUMAN (1-417): 0: 674: 100.00
+	Hs
		445643 KCRM_HUMAN (1-381): 0: 635: 80.58		KCRS_HUMAN (1-412): 0: 666: 80.15
+	Hs
		553107 KCRB_HUMAN (1-381): 0: 671: 100.00		KCRB_HUMAN (47-406): 0: 607: 69.81
+	Mm
		718751 KCRU_MOUSE (14-373): 0: 574: 69.25		KCRU_MOUSE (1-417): 0: 689: 96.65
+	Hs
		445640 KCRB_HUMAN (1-381): 0: 671: 100.00		KCRM_HUMAN (47-406): 0: 584: 67.59
+	Hs
		553781 KCRU_HUMAN (14-373): 0: 576: 69.81		KCRS_HUMAN (1-412): 0: 666: 80.15
+	Mm
		1243157 KCRS_MOUSE (14-373): 0: 574: 67.59		KCRS_MOUSE (1-412): 0: 655: 79.42
+	Mm
		718756 KCRU_MOUSE (14-373): 0: 574: 69.25		KCRS_MOUSE (1-412): 0: 655: 79.42