Protein: KCRS
Creatine kinase S-type, mitochondrial (EC 2.7.3.2) (Basic-type mitochondrial creatine kinase) (Mib-CK) (Sarcomeric mitochondrial creatine kinase) (S-MtCK)

Gene: KCRS, CKMT2
Organism: Homo sapiens
Interactions: 51
UniProt ID: P17540

Gene Ontology (top 5):
GO:0004111 - creatine kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006936 - muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

553781

KCRU
Creatine kinase U-type, mitochondrial

4

8

High-throughput

0.892

High

445643

KCRM
Creatine kinase M-type

2

8

High-throughput

0.811

High

605149

ASB9
Ankyrin repeat and SOCS box protein 9

2

6

High-throughput

0.776

High

605157

KLH42
Kelch-like protein 42

2

1

High-throughput

0.553

High

348961

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.536

High

605135

LACTB
Serine beta-lactamase-like protein LACTB, mitochondrial

1

1

High-throughput

0.536

High

605145

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

605148

COA7
Cytochrome c oxidase assembly factor 7

1

2

High-throughput

0.536

High

248194

NDK8
Putative nucleoside diphosphate kinase

2

0

High-throughput

0.528

High

584610

ELN
Elastin

1

2

High-throughput

0.494

High

605156

OLFL3
Olfactomedin-like protein 3

1

3

High-throughput

0.494

High

605130

AK1D1
Aldo-keto reductase family 1 member D1

1

1

High-throughput

0.489

High

605144

TSN33
Tetraspanin-33

1

1

High-throughput

0.489

High

605155

IKZF5
Zinc finger protein Pegasus

1

2

High-throughput

0.489

High

542322

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.479

High

605134

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

605136

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.479

High

605161

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.445

High

136822

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.437

High

303406

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.437

High

479316

SRP19
Signal recognition particle 19 kDa protein

1

1

High-throughput

0.437

High

483009

CLCA
Clathrin light chain A

1

1

High-throughput

0.437

High

605125

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.437

High

605126

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.437

High

605127

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.437

High

605128

CTCF
Transcriptional repressor CTCF

1

1

High-throughput

0.437

High

605129

MAP2
Methionine aminopeptidase 2

1

1

High-throughput

0.437

High

605132

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

1

Small-scale

0.437

High

605133

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.437

High

605138

CO4A6

1

1

High-throughput

0.437

High

605146

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.437

High

605150

DNJC2
DnaJ homolog subfamily C member 2

1

1

High-throughput

0.437

High

605151

RBM42
RNA-binding protein 42

1

3

High-throughput

0.437

High

605158

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.437

High

605159

G3BP2
Ras GTPase-activating protein-binding protein 2

1

4

High-throughput

0.437

High

605160

DRG1
Developmentally-regulated GTP-binding protein 1

1

1

High-throughput

0.437

High

605162

RBM8A
RNA-binding protein 8A

1

2

High-throughput

0.437

High

605142

RIF1
Telomere-associated protein RIF1

1

5

High-throughput

0.417

High

181607

CETN3
Centrin-3

2

0

High-throughput

0.316

High

605139

NRF1
Nuclear respiratory factor 1

2

0

High-throughput

0.316

High

605143

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

0

High-throughput

0.316

High

605137

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

605152

ABHD6
Monoacylglycerol lipase ABHD6

1

0

High-throughput

0.282

High

605153

TMED9
Transmembrane emp24 domain-containing protein 9

1

0

High-throughput

0.282

High

591467

H2AX
Histone H2AX

1

0

High-throughput

0.279

Low

605154

AP5M1
AP-5 complex subunit mu-1

1

0

High-throughput

0.279

Low

605140

FR1L6
Fer-1-like protein 6

1

0

High-throughput

0.269

Low

605141

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

192442

INSI1
Insulin-induced gene 1 protein

1

0

High-throughput

0.249

Low

605147

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.249

Low

605131

RCAN1
Calcipressin-1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025